Canadian VHL Alliance (CVHLA) Research Funding

Since 2018 we have created $240,000 in Canadian VHL research grants with our partner the Cancer Research Society!

2020  - $120,000 Research Grant Partnership

In November of 2019 the Canadian VHL Alliance (CVHLA) has entered into a second partnership with The Cancer Research Society (CRS), a Canadian based organization that will match the $60,000 CVHLA donation, to create a $120,000 grant that will be awarded in 2020.

2018  - $120,000 Research Grant Partnership

The first partnership between the CVHLA and the CRS in 2018 created a grant that was won by Dr. Najafabadi (see above for details) 

More about the Cancer Research Society (CRS)

In 2019, without a CVHLA partnership only 1 VHL related grant was submitted for CRS funding and none were approved. 

In 2018, there were 6 submissions for the CVHLA grant, two were approved!

  • An additional $120,000 of Canadian VHL research was funded in 2018 due to the CVHLA grant attracting such good submissions!

In 2017 the Cancer Research Society has funded the following projects that are related to the VHL gene and/or ccRCC:

  • Dr. Ryan Russell, University of Ottawa: Characterization of VHL-mediated RB regulation in renal cancer

  • Dr. Stefan Taubert, The University of British Columbia (UBC): Exploring Mediator-dependent stress resistance as a new target (a protein acting downstream of VHL, in the same molecular pathway)

  • Dr. Yasser Riazalhosseini, McGill University: KDM5C mutations as determinants of sex-dependent therapy in renal cell carcinoma

  • Dr. Damu Tang, McMaster University:  Characterization of CYB5D2-mediated suppression of clear cell renal cell carcinoma (ccRCC)

 

Three grants on VHL were funded by the Cancer Research Society in the past years:

  • Sandra Turcotte, U of Moncton (2012-2014): The late-stage of autophagy: A role for the tumor suppressor gene von Hippel-Lindau in lysosomal degradation

  • Amin Pause, McGill University (2006-2008): The von Hippel-Lindau (VHL) protein suppresses angiogenesis by maintaining extracellular matrix integrity

  • Stephen Lee, University of Ottawa (2004-2006): Dissecting the oncogenic pathway of VHL loss kidney cancer

Our CVHLA goal is to apply a very large percentage of our donations directly to funding Research Projects.    

The video below describes a research project the US based VHL Alliance has funded. The CVHLA has supported these efforts in the past.